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Cxcl16 Antibody (PACO32696)

SKU:
PACO32696
Product Type:
Antibody
Reactivity:
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€339
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Description

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Cxcl16 Antibody (PACO32696)

The CXCL16 Antibody (PAC032696) is a valuable tool for researchers studying CXCL16, a chemokine protein involved in immune responses and inflammation. This polyclonal antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By binding to the CXCL16 protein, it allows for the detection and analysis of CXCL16 in various cell types, making it an excellent choice for studies in immunology and inflammatory diseases.CXCL16 is a multifunctional chemokine that acts as both a chemoattractant for immune cells and a cell-adhesion molecule, playing a crucial role in the recruitment and activation of immune cells in response to infection or injury.

Its involvement in inflammatory processes makes it a key target for research in diseases such as rheumatoid arthritis, atherosclerosis, and cancer. Understanding the function of CXCL16 is essential for developing targeted therapies that modulate immune responses in these conditions.Overall, the CXCL16 Antibody (PAC032696) offers researchers a reliable and specific tool for investigating the role of CXCL16 in immune regulation and inflammation, paving the way for advancements in the treatment of inflammatory diseases.

Antibody Name:Cxcl16 Antibody (PACO32696)
Antibody SKU:PACO32696
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA
Recommended Dilutions:
Species Reactivity:Mouse
Immunogen:Recombinant Mouse C-X-C motif chemokine 16 protein (27-198AA)
Form:Liquid
Storage Buffer:Preservative: 0.03% Proclin 300
Constituents: 50% Glycerol, 0.01M PBS, PH 7.4
Purification Method:>95%, Protein G purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:C-X-C motif chemokine 16 (Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein) (SR-PSOX) (Small-inducible cytokine B16) (Transmembrane chemokine CXCL16), Cxcl16, Srpsox
UniProt Protein Function:CXCL16: Acts as a scavenger receptor on macrophages, which specifically binds to OxLDL (oxidized low density lipoprotein), suggesting that it may be involved in pathophysiology such as atherogenesis. Induces a strong chemotactic response. Induces calcium mobilization. Binds to CXCR6/Bonzo. Belongs to the intercrine alpha (chemokine CxC) family.
UniProt Protein Details:

Protein type:Membrane protein, integral

Cellular Component: extracellular space; membrane; integral to membrane

Molecular Function:low-density lipoprotein receptor activity; chemokine receptor binding; chemokine activity; cytokine activity; scavenger receptor activity

Biological Process: receptor-mediated endocytosis; response to cytokine stimulus; chemotaxis; lymphocyte chemotaxis; positive regulation of cell growth; positive regulation of cell migration

UniProt Code:Q8BSU2
NCBI GenInfo Identifier:37088434
NCBI Gene ID:66102
NCBI Accession:Q8BSU2.2
UniProt Secondary Accession:Q8BSU2,Q3UD70, Q5F2D5, Q8VE25, Q9EPB3,
UniProt Related Accession:Q8BSU2
Molecular Weight:26,896 Da
NCBI Full Name:C-X-C motif chemokine 16
NCBI Synonym Full Names:chemokine (C-X-C motif) ligand 16
NCBI Official Symbol:Cxcl16  
NCBI Official Synonym Symbols:SR-PSOX; Zmynd15; AV290116; BB024863; CXCL16v1; CXCL16v2; b2b498Clo; 0910001K24Rik  
NCBI Protein Information:C-X-C motif chemokine 16; SR-PSOX/CXCL16; Mutant line 498; Cxc chemokine ligand 16; small-inducible cytokine B16; transmembrane chemokine CXCL16; zinc finger, MYND-type containing 15; scavenger receptor for phosphatidylserine and oxidized low density lipoprotein
UniProt Protein Name:C-X-C motif chemokine 16
UniProt Synonym Protein Names:Scavenger receptor for phosphatidylserine and oxidized low density lipoprotein; SR-PSOX; Small-inducible cytokine B16; Transmembrane chemokine CXCL16
Protein Family:C-X-C motif chemokine
UniProt Gene Name:Cxcl16  
UniProt Entry Name:CXL16_MOUSE

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