The CXCL12 Rabbit Polyclonal Antibody (CAB18225) is a valuable tool for researchers interested in studying CXCL12, a chemokine involved in immune responses and cell migration. This antibody, produced in rabbits, is highly sensitive and specific for detecting CXCL12 in human samples, making it ideal for use in Western blotting applications.CXCL12, also known as stromal cell-derived factor 1 (SDF-1), plays a crucial role in various physiological processes, including immune cell trafficking, angiogenesis, and stem cell homing. It is implicated in a wide range of diseases, including cancer, HIV/AIDS, and inflammatory conditions.
The ability to accurately detect and quantify CXCL12 levels with this antibody provides researchers with a valuable tool for exploring its role in these disease processes.By using the CXCL12 Rabbit Polyclonal Antibody (CAB18225), researchers can gain insight into the molecular mechanisms underlying CXCL12 function and potentially identify new therapeutic targets for diseases characterized by dysregulated CXCL12 signaling. Its high specificity and sensitivity make it a reliable tool for investigating the role of CXCL12 in various biological processes, making it a valuable asset for immunology and cancer research.
Product Name:
CXCL12 Rabbit Polyclonal Antibody
SKU:
CAB18225
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 40-93 of human CXCL12 (NP_000600.1).
This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6387
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using CXCL12 Rabbit pAb (CAB18225) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 3min.
