The CXCL12 Polyclonal Antibody (CAB1325) is a valuable tool for researchers studying CXCL12, a chemokine protein known for its role in immune response and inflammation. Raised in rabbits, this antibody is highly specific and reactive with human samples, making it ideal for use in various research applications. CXCL12, also known as stromal cell-derived factor 1 (SDF-1), is involved in a wide range of biological processes, including immune cell trafficking, hematopoiesis, angiogenesis, and tissue repair. Its expression is associated with various diseases, including cancer, inflammation, and autoimmune disorders.
The CXCL12 Polyclonal Antibody enables detection and analysis of CXCL12 protein levels in different cell types and tissues, providing researchers with valuable insights into its function and potential therapeutic targets.Whether studying immune cell migration, tumor microenvironment interactions, or inflammatory responses, the CXCL12 Polyclonal Antibody is a reliable tool for researchers looking to delve deeper into the molecular mechanisms underlying these biological processes. Its specificity and sensitivity make it a valuable asset for studies in immunology, oncology, and inflammation research.
Product Name:
CXCL12 Rabbit Polyclonal Antibody
SKU:
CAB1325
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 40-93 of human CXCL12 (NP_000600.1).
This antimicrobial gene encodes a stromal cell-derived alpha chemokine member of the intercrine family. The encoded protein functions as the ligand for the G-protein coupled receptor, chemokine (C-X-C motif) receptor 4, and plays a role in many diverse cellular functions, including embryogenesis, immune surveillance, inflammation response, tissue homeostasis, and tumor growth and metastasis. Mutations in this gene are associated with resistance to human immunodeficiency virus type 1 infections. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
6387
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of lysates from Mouse kidney, using CXCL12 Rabbit pAb (CAB1325) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 180s.
