The CXCL10 Polyclonal Antibody (CAB1457) is a valuable tool for researchers studying CXCL10, a chemokine involved in immune responses, inflammation, and cancer progression. This antibody, produced in rabbits, is specifically designed to target the CXCL10 protein, allowing for accurate detection and analysis in various experimental settings, including Western blot applications.CXCL10, also known as interferon-gamma-induced protein 10 (IP-10), is a key player in recruiting immune cells to sites of inflammation and promoting anti-tumor immunity. Its dysregulation has been implicated in various diseases, including autoimmune disorders, infectious diseases, and cancer.
By utilizing the CXCL10 Polyclonal Antibody, researchers can gain valuable insights into the role of CXCL10 in these conditions and potentially identify new therapeutic targets.Overall, the CXCL10 Polyclonal Antibody (CAB1457) is an essential tool for studying the function of CXCL10 and its impact on immune responses and disease progression. Its high reactivity with human samples makes it an ideal choice for researchers in the fields of immunology, oncology, and inflammatory diseases.
Product Name:
CXCL10 Rabbit Polyclonal Antibody
SKU:
CAB1457
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-98 of human CXCL10/IP-10 (NP_001556.2).
This antimicrobial gene encodes a chemokine of the CXC subfamily and ligand for the receptor CXCR3. Binding of this protein to CXCR3 results in pleiotropic effects, including stimulation of monocytes, natural killer and T-cell migration, and modulation of adhesion molecule expression. This gene may also be a key regulator of the 'cytokine storm' immune response to SARS-CoV-2 infection.
Purification Method:
Affinity purification
Gene ID:
3627
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of HeLa cells, using CXCL10/IP-10 antibody (CAB1457).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.
