The CXCL1 Polyclonal Antibody (CAB5802) is a valuable tool for researchers studying CXCL1, a chemokine involved in inflammation and immune response. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CXCL1 protein, this antibody enables the detection and analysis of CXCL1 in a variety of cell types, making it an ideal choice for studies in immunology and cancer research.CXCL1, also known as GRO alpha, plays a crucial role in recruiting neutrophils to sites of inflammation, promoting angiogenesis, and enhancing cancer cell proliferation and metastasis.
Understanding the function and regulation of CXCL1 is essential for developing targeted therapies for diseases such as cancer, inflammatory disorders, and autoimmune conditions. The CXCL1 Polyclonal Antibody provides researchers with a reliable tool for investigating the role of CXCL1 in these diseases and identifying potential therapeutic targets.
Product Name:
GRO alpha Rabbit Polyclonal Antibody
SKU:
CAB5802
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 1-107 of human GRO alpha (NP_001502.1).
This antimicrobial gene encodes a member of the CXC subfamily of chemokines. The encoded protein is a secreted growth factor that signals through the G-protein coupled receptor, CXC receptor 2. This protein plays a role in inflammation and as a chemoattractant for neutrophils. Aberrant expression of this protein is associated with the growth and progression of certain tumors. A naturally occurring processed form of this protein has increased chemotactic activity. Alternate splicing results in coding and non-coding variants of this gene. A pseudogene of this gene is found on chromosome 4.
Purification Method:
Affinity purification
Gene ID:
2919
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of extracts of NCI-H460 cells, using GRO alpha antibody (CAB5802) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
