The CXADR Polyclonal Antibody (CAB1822) is a valuable tool for researchers studying CXADR, a key protein involved in cell adhesion and viral infection. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.CXADR, also known as Coxsackie and adenovirus receptor, plays a crucial role in facilitating entry of certain viruses into host cells, making it a potential target for understanding viral pathogenesis and developing antiviral therapies. By binding to the CXADR protein, this antibody enables researchers to detect and analyze CXADR expression in various cell types, allowing for in-depth studies in virology and infectious disease research.
Given its importance in viral infection mechanisms, the CXADR Polyclonal Antibody is an essential tool for advancing knowledge in the fields of virology, immunology, and molecular biology. Its application in research may lead to the discovery of novel strategies for combating viral diseases and enhancing our understanding of host-pathogen interactions.
Product Name:
CXADR Rabbit Polyclonal Antibody
SKU:
CAB1822
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-237 of human CAR/CXADR (NP_001329.1).
Basolateral cell membrane, Cell junction, Cell membrane, Secreted, Single-pass membrane protein, Single-pass type I membrane protein, Single-pass type I membrane protein, adherens junction, tight junction.
Calculated MW:
40kDa
Observed MW:
50kDa
The protein encoded by this gene is a type I membrane receptor for group B coxsackieviruses and subgroup C adenoviruses. Several transcript variants encoding different isoforms have been found for this gene. Pseudogenes of this gene are found on chromosomes 15, 18, and 21.
Purification Method:
Affinity purification
Gene ID:
1525
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CAR/CXADR antibody (CAB1822) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 3s.