The CX3CR1 Polyclonal Antibody (CAB2890) is a valuable tool for researchers studying the CX3CR1 protein, a cell surface receptor involved in immune regulation and inflammatory responses. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By targeting the CX3CR1 protein, researchers can effectively detect and analyze its expression in various cell types, making it an essential component for studies in immunology, inflammation, and related research fields.CX3CR1, also known as fractalkine receptor, plays a crucial role in mediating the adhesion and migration of immune cells to sites of inflammation.
Its involvement in immune cell recruitment and activation highlights its significance in regulating immune responses and inflammatory processes. Research on CX3CR1 is vital for understanding its functions in diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions, providing insight into potential therapeutic strategies that target immune cell trafficking and activation.
Product Name:
CX3CR1 Rabbit Polyclonal Antibody
SKU:
CAB2890
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 100-200 of human CX3CR1 (NP_001328.1).
Fractalkine is a transmembrane protein and chemokine involved in the adhesion and migration of leukocytes. The protein encoded by this gene is a receptor for fractalkine. The encoded protein also is a coreceptor for HIV-1, and some variations in this gene lead to increased susceptibility to HIV-1 infection and rapid progression to AIDS. Four transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1524
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates using CX3CR1 Rabbit pAb (CAB2890) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
