The CWC22 Polyclonal Antibody (CAB13116) is a valuable tool for researchers studying the CWC22 protein, which is involved in mRNA splicing and processing. This antibody, produced in rabbits, exhibits high reactivity with human samples and is suitable for use in Western blot applications. By specifically binding to the CWC22 protein, researchers can efficiently detect and analyze its expression in various cell types, making it an essential component for studies in molecular biology and gene expression regulation.CWC22 is a key player in the spliceosome complex, which is responsible for correctly removing introns from pre-mRNA during transcription.
Dysregulation of splicing processes can lead to various diseases, including cancer and genetic disorders. Therefore, investigating the role of CWC22 in splicing can provide valuable insights into disease mechanisms and potential therapeutic targets.Overall, the CWC22 Polyclonal Antibody (CAB13116) is a reliable tool for researchers interested in unraveling the intricacies of mRNA splicing and its implications in disease pathogenesis and therapy development.
Product Name:
CWC22 Rabbit Polyclonal Antibody
SKU:
CAB13116
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 639-908 of human CWC22 (NP_065994.1).
Enables RNA binding activity. Involved in mRNA splicing, via spliceosome. Located in cytosol and nuclear speck. Part of U2-type catalytic step 1 spliceosome; U2-type catalytic step 2 spliceosome; and U2-type precatalytic spliceosome.
Purification Method:
Affinity purification
Gene ID:
57703
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CWC22 Rabbit pAb (CAB13116) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
