CUL4B Rabbit Polyclonal Antibody (CAB5400)
- SKU:
- CAB5400
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | CUL4B Rabbit Polyclonal Antibody |
SKU: | CAB5400 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 1-200 of human CUL4B (NP_003579.3). |
Sequence: | MMSQ SSGS GDGN DDEA TTSK DGGF SSPS PSAA AAAQ EVRS ATDG NTST TPPT SAKK RKLN SSSS SSSN SSNE REDF DSTS SSSS TPPL QPRD SASP STSS FCLG VSVA ASSH VPIQ KKLR FEDT LEFV GFDA KMAE ESSS SSSS SSPT AATS QQQQ LKNK SILI SSVA SVHH ANGL AKSS TTVS SFAN SKPG SAKK LVIK |
Tested Applications: | WB IHC-P IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 |
Synonyms: | SFM2; MRXSC; CUL-4B; MRXHF2; MRXS15; CUL4B |
Positive Sample: | Mouse liver,Mouse kidney |
Conjugate: | Unconjugated |
Cellular Localization: | Nucleus. |
Calculated MW: | 104kDa |
Observed MW: | 115kDa |
This gene is a member of the cullin family. The encoded protein forms a complex that functions as an E3 ubiquitin ligase and catalyzes the polyubiquitination of specific protein substrates in the cell. The protein interacts with a ring finger protein, and is required for the proteolysis of several regulators of DNA replication including chromatin licensing and DNA replication factor 1 and cyclin E. Multiple transcript variants encoding different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8450 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |