The Cullin-3 Rabbit Monoclonal Antibody (CAB19623) is a high-quality antibody designed for research involving Cullin-3, a key component of the Cullin-RING family of E3 ubiquitin ligases. This antibody, generated in rabbits, is highly specific and reactive with human samples, making it an excellent tool for Western blot applications.Cullin-3 plays a crucial role in protein degradation and the regulation of various cellular processes, including cell cycle progression and signaling pathways. By targeting Cullin-3 with this antibody, researchers can investigate its function and interactions in different cell types, offering valuable insights into its role in cellular homeostasis and disease development.
The Cullin-3 Rabbit Monoclonal Antibody is an essential tool for studies in cell biology, cancer research, and drug development, providing researchers with a reliable means to detect and analyze Cullin-3 expression levels in various experimental settings. Its high specificity and sensitivity make it an ideal choice for researchers aiming to uncover the molecular mechanisms underlying cellular processes regulated by Cullin-3.
Product Name:
Cullin 3 Rabbit Monoclonal Antibody
SKU:
CAB19623
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 669-768 of human Cullin 3 (Q13618).
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method:
Affinity purification
Gene ID:
8452
Clone Number:
ARC0102
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cullin 3 Rabbit mAb (CAB19623) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
