Cullin 3 Rabbit Polyclonal Antibody (CAB1078)
- SKU:
- CAB1078
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | Cullin 3 Rabbit Polyclonal Antibody |
SKU: | CAB1078 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 468-768 of human Cullin 3 (NP_003581.1). |
Sequence: | SKLE GMFR DMSI SNTT MDEF RQHL QATG VSLG GVDL TVRV LTTG YWPT QSAT PKCN IPPA PRHA FEIF RRFY LAKH SGRQ LTLQ HHMG SADL NATF YGPV KKED GSEV GVGG AQVT GSNT RKHI LQVS TFQM TILM LFNN REKY TFEE IQQE TDIP EREL VRAL QSLA CGKP TQRV LTKE PKSK EIEN GHIF TVND QFTS KLHR VKIQ TVAA KQGE SDPE RKET RQKV DDDR KHEI EAAI VRIM KSRK KMQH NVLV AEVT QQLK ARFL PSPV VIKK RIEG LIER EYLA RTPE DRKV YTYV A |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | CUL-3; PHA2E; NEDAUS; Cullin 3 |
Positive Sample: | MCF7,Mouse testis,Mouse brain,Mouse spleen,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus, Nucleus. |
Calculated MW: | 89kDa |
Observed MW: | 84kDa |
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8452 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |