Cullin 3 Rabbit Polyclonal Antibody (CAB16455)
- SKU:
- CAB16455
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Cycle
Frequently bought together:
Description
Product Name: | Cullin 3 Rabbit Polyclonal Antibody |
SKU: | CAB16455 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 569-768 of human Cullin 3 (NP_003581.1). |
Sequence: | KEDG SEVG VGGA QVTG SNTR KHIL QVST FQMT ILML FNNR EKYT FEEI QQET DIPE RELV RALQ SLAC GKPT QRVL TKEP KSKE IENG HIFT VNDQ FTSK LHRV KIQT VAAK QGES DPER KETR QKVD DDRK HEIE AAIV RIMK SRKK MQHN VLVA EVTQ QLKA RFLP SPVV IKKR IEGL IERE YLAR TPED RKVY TYVA |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IF/ICC,1:50 - 1:200 |
Synonyms: | CUL-3; PHA2E; NEDAUS; Cullin 3 |
Positive Sample: | U-251MG,HeLa,MCF7,Mouse brain,Mouse spleen,Mouse testis,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Golgi apparatus, Nucleus. |
Calculated MW: | 89kDa |
Observed MW: | 82kDa |
This gene encodes a member of the cullin protein family. The encoded protein plays a critical role in the polyubiquitination and subsequent degradation of specific protein substrates as the core component and scaffold protein of an E3 ubiquitin ligase complex. Complexes including the encoded protein may also play a role in late endosome maturation. Mutations in this gene are a cause of type 2E pseudohypoaldosteronism. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene.
Purification Method: | Affinity purification |
Gene ID: | 8452 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |