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CTSL1 Monoclonal Antibody [P2H7AT] (CPAB0142)

SKU:
CPAB0142
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2b
Clone:
P2H7AT
Applications:
WB
ELISA
€149
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Description

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CTSL1 Monoclonal Antibody [P2H7AT] (CPAB0142)

The CTSL1 Antibody (CPAB0142) is a polyclonal antibody designed for research involving cathepsin L1 (CTSL1), a lysosomal cysteine protease involved in various cellular processes, including protein degradation and tissue remodeling. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot and immunohistochemistry applications.CTSL1 is known to play a crucial role in tumor progression and metastasis in various types of cancer, making it a compelling target for cancer research. By binding to the CTSL1 protein, this antibody enables the detection and analysis of CTSL1 expression in different cell types, providing valuable insights into the molecular mechanisms underlying cancer development and progression.

Furthermore, CTSL1 has also been implicated in other physiological and pathological processes, such as immune response regulation and tissue repair. Research on CTSL1 using this antibody may contribute to a better understanding of its functions in various biological contexts and ultimately facilitate the development of novel therapeutic strategies for cancer and other related conditions.

Product Name:CTSL1 Antibody
Product Sku:CPAB0142
Size:5μg
Host Species:Mouse
Immunogen:Anti-human Cathepsin-L mAb is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human Cathepsin-L amino acids 114-333 purified from Ecoli.
Clone:P2H7AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:Cathepsin-L antibody was purified from mouse ascitic fluids by protein-G affinity chromatography.
Isotype:IgG2b
Background:Cathepsins B, C, H, L, S, V, X/Z/P and 1 are cysteine proteases of the papain family. Cathepsin C is also known as DPPI (dipeptidyl-peptidase I). Cathepsin A is a serine carboxypeptidase and Cathepsin D and E are aspartic proteases. As lysosomal proteases, cathepsins play an important role in protein degradation. Because of their redistribution or increased levels in human and animal tumors, cathepsins may have a role in invasion and metastasis. Cathepsins are synthesized as inactive proenzymes and processed to become mature and active enzymes. Endogenous protein inhibitors, such as cystatins and some serpins, inhibit active enzymes.
Synonyms:Cathepsin L1, EC 3.4.22.15, Major excreted protein, MEP, CTSL1, CTSL, CATL, FLJ31037.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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