CTSL Antibody (PACO26037)
- SKU:
- PACO26037
- Product Type:
- Antibody
- Reactivity:
- NHP - Monkey
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- WB
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
CTSL Antibody (PACO26037)
The CTSL Polyclonal Antibody (PAC026037) is a key tool for researchers studying cathepsin L (CTSL), a lysosomal cysteine protease involved in various physiological processes and linked to diseases such as cancer and neurodegenerative disorders. This antibody, developed using rabbit immunization, exhibits high specificity and sensitivity for detecting CTSL in human samples, making it suitable for techniques like Western blotting.CTSL is known for its role in protein degradation, antigen processing, and tissue remodeling, with dysregulation of its activity implicated in various pathological conditions. By targeting CTSL with this antibody, researchers can investigate its expression levels, localization, and interactions in different cell types, providing valuable insights into its function and potential therapeutic implications.
The CTSL Polyclonal Antibody is a valuable tool for researchers exploring the intricate mechanisms of CTSL in health and disease, with the aim of developing targeted interventions for conditions associated with dysregulated protease activity. Its reliability and specificity make it a trusted reagent for studies in molecular biology, biochemistry, and drug development focused on understanding and manipulating CTSL function.
| Antibody Name: | CTSL Antibody (PACO26037) |
| Antibody SKU: | PACO26037 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA, WB |
| Recommended Dilutions: | ELISA:1:2000-1:10000, WB:1:1000-1:5000 |
| Species Reactivity: | Chlorocebus aethiops, Human |
| Immunogen: | Recombinant Chlorocebus aethiops Cathepsin L1 protein (114-333AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
 | Western blot All lanes: CTSL antibody at 12µg/ml Lane 1: A549 whole cell lysate Lane 2: HepG2 whole cell lysate Secondary Goat polyclonal to rabbit IgG at 1/10000 dilution Predicted band size: 38 kDa Observed band size: 38 kDa . |
| Background: | Important for the overall degradation of proteins in lysosomes. |
| Synonyms: | Cathepsin L1 (EC 3.4.22.15) (Cathepsin L) (Major excreted protein) (MEP) [Cleaved into: Cathepsin L1 heavy chain; Cathepsin L1 light chain], CTSL, CTSL1 |
| UniProt Protein Function: | Important for the overall degradation of proteins in lysosomes. |
| UniProt Protein Details: | |
| NCBI Summary: | |
| UniProt Code: | Q9GKL8 |
| NCBI GenInfo Identifier: | 75067394 |
| NCBI Gene ID: | |
| NCBI Accession: | Q9GKL8.1 |
| UniProt Secondary Accession: | Q9GKL8 |
| UniProt Related Accession: | Q9GKL8 |
| Molecular Weight: | 37,430 Da |
| NCBI Full Name: | Cathepsin L1 |
| NCBI Synonym Full Names: | |
| NCBI Official Symbol: | |
| NCBI Official Synonym Symbols: | |
| NCBI Protein Information: | |
| UniProt Protein Name: | Cathepsin L1 |
| UniProt Synonym Protein Names: | Cathepsin L; Major excreted protein; MEP |
| Protein Family: | |
| UniProt Gene Name: | CTSLÂ Â |
| UniProt Entry Name: | CATL1_CHLAE |
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