The CTSG Polyclonal Antibody (CAB13172) is a valuable tool for researchers studying Cathepsin G (CTSG), a serine protease involved in immune response and inflammation. This antibody, generated in rabbits, is highly specific to human samples and is validated for Western blot applications. By binding to CTSG, the antibody enables accurate detection and analysis of this protein in various cell types, making it ideal for research in immunology, inflammation, and diseases like cancer.CTSG is known for its role in immune cell function, particularly in neutrophils where it participates in processes like antimicrobial defense and inflammation regulation.
Dysregulation of CTSG has been linked to various diseases, making it a promising target for therapeutic intervention. Understanding the function and regulation of CTSG is crucial for developing strategies to modulate immune responses and potentially treat conditions characterized by inflammation and immune dysfunction.
Product Name:
CTSG Rabbit Polyclonal Antibody
SKU:
CAB13172
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 75-190 of human Cathepsin G (NP_001902.1).
The protein encoded by this gene, a member of the peptidase S1 protein family, is found in azurophil granules of neutrophilic polymorphonuclear leukocytes. The encoded protease has a specificity similar to that of chymotrypsin C, and may participate in the killing and digestion of engulfed pathogens, and in connective tissue remodeling at sites of inflammation. In addition, the encoded protein is antimicrobial, with bacteriocidal activity against S. aureus and N. gonorrhoeae. Transcript variants utilizing alternative polyadenylation signals exist for this gene.
Purification Method:
Affinity purification
Gene ID:
1511
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using Cathepsin G Rabbit pAb (CAB13172) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
