Ctsg Antibody (PACO26029)
- SKU:
- PACO26029
- Product Type:
- Antibody
- Reactivity:
- Mouse
- Host Species:
- Rabbit
- Isotype:
- IgG
- Applications:
- ELISA
- Antibody Type:
- Polyclonal Antibody
- Conjugation:
- Unconjugated
Description
Ctsg Antibody (PACO26029)
The CTSG Polyclonal Antibody (PACO26029) is an essential tool for researchers studying Cathepsin G (CTSG), a serine protease enzyme involved in immune response regulation. This polyclonal antibody, generated in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications. By specifically binding to the CTSG protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it an invaluable asset for studies in immunology and inflammatory diseases.CTSG is known for its role in immune system modulation, particularly in the activation and regulation of neutrophils during inflammatory responses.
Its involvement in various immune processes makes it a promising target for research in conditions such as sepsis, arthritis, and cardiovascular diseases. By understanding the function and regulation of CTSG, researchers can gain insights into the underlying mechanisms of these diseases and potentially develop novel therapeutic interventions targeting this enzyme.Overall, the CTSG Polyclonal Antibody (PACO26029) provides researchers with a reliable tool for investigating the role of CTSG in immune regulation and inflammatory diseases, paving the way for advancements in both basic science and clinical research.
| Antibody Name: | Ctsg Antibody (PACO26029) |
| Antibody SKU: | PACO26029 |
| Size: | 50ug |
| Host Species: | Rabbit |
| Tested Applications: | ELISA |
| Recommended Dilutions: | |
| Species Reactivity: | Mouse |
| Immunogen: | Recombinant Mouse Cathepsin G protein (21-261AA) |
| Form: | Liquid |
| Storage Buffer: | Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 |
| Purification Method: | >95%, Protein G purified |
| Clonality: | Polyclonal |
| Isotype: | IgG |
| Conjugate: | Non-conjugated |
| Background: | This vimentin-specific protease may regulate the reorganization of vimentin filaments, occurring during cell differentiation, movement and mitosis. |
| Synonyms: | Cathepsin G (EC 3.4.21.20) (Vimentin-specific protease) (VSP), Ctsg |
| UniProt Protein Function: | CTSG: Serine protease with trypsin- and chymotrypsin-like specificity. Cleaves complement C3. Has antibacterial activity against the Gram-negative bacterium P.aeruginosa, antibacterial activity is inhibited by LPS from P.aeruginosa, Z-Gly-Leu-Phe- CH2Cl and phenylmethylsulfonyl fluoride. Belongs to the peptidase S1 family. |
| UniProt Protein Details: | Protein type:Motility/polarity/chemotaxis; EC 3.4.21.20; Protease Cellular Component: cytoplasm; extracellular matrix; extracellular space; intermediate filament; intracellular membrane-bound organelle; membrane; nucleus; plasma membrane; secretory granule Molecular Function:heparin binding; hydrolase activity; peptidase activity; serine-type endopeptidase activity; serine-type peptidase activity Biological Process: defense response to fungus; defense response to Gram-positive bacterium; immune response; positive regulation of immune response; protein amino acid phosphorylation; protein processing; proteolysis; response to lipopolysaccharide |
| NCBI Summary: | This gene encodes a member of the peptidase S1 (chymotrypsin) family of serine endopeptidases. The encoded preproprotein is proteolytically processed to generate a mature protein product. This product appears to play a role in host defense, including inflammation and antigen processing. Homozygous knockout mice for this gene exhibit enhanced susceptibility to bacterial and fungal infection. [provided by RefSeq, Aug 2015] |
| UniProt Code: | P28293 |
| NCBI GenInfo Identifier: | 6681083 |
| NCBI Gene ID: | 13035 |
| NCBI Accession: | NP_031826.1 |
| UniProt Related Accession: | P28293 |
| Molecular Weight: | 42.9 kDa |
| NCBI Full Name: | cathepsin G preproprotein |
| NCBI Synonym Full Names: | cathepsin G |
| NCBI Official Symbol: | Ctsg  |
| NCBI Official Synonym Symbols: | VSP; CatGÂ Â |
| NCBI Protein Information: | cathepsin G |
| UniProt Protein Name: | Cathepsin G |
| UniProt Synonym Protein Names: | Vimentin-specific protease; VSP |
| Protein Family: | Cathepsin |
| UniProt Gene Name: | Ctsg  |
| UniProt Entry Name: | CATG_MOUSE |
Related Products
CTSG Rabbit Polyclonal Antibody (CAB13172)
CTSG Rabbit Polyclonal Antibody (CAB5636)
Human Cathepsin G Antibody(CTSG Ab) ELISA kit
Human Cathepsin G (CTSG) ELISA Kit (HUEB1906)
Rat Cathepsin G (Ctsg) ELISA Kit (RTEB1179)
Mouse CTSG (Cathepsin G) ELISA Kit (MOES01827)
