The CTSA Polyclonal Antibody (CAB5503) is a crucial tool for researchers studying the CTSA protein, which is involved in various cellular processes, including lysosomal degradation and protein trafficking. The antibody is sourced from rabbits and exhibits high reactivity with human samples, making it an ideal choice for Western blot applications.CTSA, also known as carboxypeptidase C, plays a key role in the proper functioning of lysosomes and is essential for the degradation of cellular waste. Dysregulation of CTSA has been linked to various diseases, including lysosomal storage disorders and neurodegenerative conditions.
By targeting CTSA with this polyclonal antibody, researchers can better understand its functions and its potential role in disease pathology.The CTSA Polyclonal Antibody (CAB5503) is a valuable tool for researchers in the fields of biochemistry, cell biology, and molecular biology, looking to investigate the role of CTSA in health and disease. Its high specificity and sensitivity make it a reliable choice for detecting and analyzing CTSA in a variety of sample types, paving the way for new insights and potential therapeutic targets.
Product Name:
CTSA Rabbit Polyclonal Antibody
SKU:
CAB5503
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 210-450 of human CTSA (NP_001121167.1).
This gene encodes a member of the peptidase S10 family of serine carboxypeptidases. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed to generate two chains that comprise the heterodimeric active enzyme. This enzyme possesses deamidase, esterase and carboxypeptidase activities and acts as a scaffold in the lysosomal multienzyme complex. Mutations in this gene are associated with galactosialidosis.
Purification Method:
Affinity purification
Gene ID:
5476
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CTSA antibody (CAB5503) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 180s.
