The CTPS1 Polyclonal Antibody (CAB3817) is a valuable tool for researchers studying CTPS1, an essential enzyme involved in pyrimidine biosynthesis. This antibody, produced in rabbits, shows high reactivity with human samples and is suitable for use in Western blot applications. By binding specifically to the CTPS1 protein, this antibody enables precise detection and analysis in various cell types, making it an ideal choice for studies in molecular biology and cancer research.CTPS1, also known as CTP synthase 1, is a key enzyme in the de novo synthesis of CTP, a crucial building block for DNA and RNA. Dysregulation of CTPS1 has been implicated in various diseases, including cancer, autoimmune disorders, and metabolic disorders.
Research into the role of CTPS1 can provide valuable insights into the mechanisms underlying these conditions and may pave the way for the development of targeted therapies.By utilizing the CTPS1 Polyclonal Antibody (CAB3817), researchers can effectively study the expression and function of CTPS1 in different cellular contexts, advancing our understanding of its role in health and disease. This antibody is a reliable tool for investigating the molecular mechanisms that govern pyrimidine metabolism and holds promise for the development of novel therapeutic strategies.
Product Name:
CTPS1 Rabbit Polyclonal Antibody
SKU:
CAB3817
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 402-591 of human CTPS1 (NP_001896.2).
This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1503
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CTPS1 Rabbit pAb (CAB3817) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
