The Anti-CTP Synthase (CTPS) Antibody (CAB20912) is a valuable tool for researchers studying CTPS, a key enzyme involved in nucleotide biosynthesis. This polyclonal antibody, generated in rabbits, is highly specific to human CTPS and has been validated for use in Western blot applications. By targeting the CTPS protein, this antibody allows for the accurate detection and analysis of CTPS expression in various cell types.CTPS plays a crucial role in the production of CTP, a critical building block for DNA and RNA synthesis. Dysregulation of CTPS has been implicated in various diseases, including cancer and autoimmune disorders, making it an attractive target for therapeutic intervention.
Understanding the expression and activity of CTPS is essential for unraveling its role in disease pathology and identifying potential treatment strategies.Researchers in the fields of molecular biology, cancer biology, and drug development will find the Anti-CTP Synthase (CTPS) Antibody (CAB20912) to be a valuable asset in their studies. Its high specificity and sensitivity make it an ideal tool for investigating the function of CTPS and its potential as a therapeutic target.
Product Name:
CTP synthase/CTPS Monoclonal Antibody
SKU:
CAB20912
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 200-300 of human CTP synthase / CTPS (P17812).
This gene encodes an enzyme responsible for the catalytic conversion of UTP (uridine triphosphate) to CTP (cytidine triphospate). This reaction is an important step in the biosynthesis of phospholipids and nucleic acids. Activity of this proten is important in the immune system, and loss of function of this gene has been associated with immunodeficiency. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1503
Clone Number:
ARC2883
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CTP synthase/CTPS antibody (CAB20912) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
