CTNND2 Rabbit Polyclonal Antibody (CAB12633)
- SKU:
- CAB12633
- Product Type:
- Antibody
- Reactivity:
- Human
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Antibody Type:
- Polyclonal Antibody
- Research Area:
- Cell Biology
Frequently bought together:
Description
Product Name: | CTNND2 Rabbit Polyclonal Antibody |
SKU: | CAB12633 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Rat |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 966-1225 of human CTNND2 (NP_001323.1). |
Sequence: | TLHE VITK NMEN AKAL RDAG GIEK LVGI SKSK GDKH SPKV VKAA SQVL NSMW QYRD LRSL YKKD GWSQ YHFV ASSS TIER DRQR PYSS SRTP SISP VRVS PNNR SASA PASP REMI SLKE RKTD YECT GSNA TYHG AKGE HTSR KDAM TAQN TGIS TLYR NSYG APAE DIKH NQVS AQPV PQEP SRKD YETY QPFQ NSTR NYDE SFFE DQVH HRPP ASEY TMHL GLKS TGNY VDFY SAAR PYSE LNYE TSHY PASP DSWV |
Tested Applications: | WB ELISA |
Recommended Dilution: | WB,1:1000 - 1:3000 |
Synonyms: | GT24; NPRAP; CTNND2 |
Positive Sample: | PC-12 |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Cell projection, Nucleus, Perikaryon, adherens junction, dendrite. |
Calculated MW: | 133kDa |
Observed MW: | 129kDa |
This gene encodes an adhesive junction associated protein of the armadillo/beta-catenin superfamily and is implicated in brain and eye development and cancer formation. The protein encoded by this gene promotes the disruption of E-cadherin based adherens junction to favor cell spreading upon stimulation by hepatocyte growth factor. This gene is overexpressed in prostate adenocarcinomas and is associated with decreased expression of tumor suppressor E-cadherin in this tissue. This gene resides in a region of the short arm of chromosome 5 that is deleted in Cri du Chat syndrome. Alternative splicing results in multiple transcript variants encoding different isoforms.
Purification Method: | Affinity purification |
Gene ID: | 1501 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |