The CTNNA3 Polyclonal Antibody (CAB16519) is a valuable tool for researchers studying CTNNA3, a protein associated with cell-cell adhesion and signaling pathways. This antibody, generated in rabbits, exhibits high specificity and sensitivity in detecting CTNNA3 in various biological samples, particularly human tissues. Validated for use in Western blot applications, it efficiently binds to the CTNNA3 protein, enabling precise analysis and visualization in a variety of cell types.CTNNA3, also known as alpha-T catenin, is crucial for maintaining tissue integrity and regulating cellular processes such as cell migration and differentiation.
Dysregulation of CTNNA3 has been linked to several diseases, including cancer and developmental disorders. By studying the role of CTNNA3 in these conditions, researchers can uncover new insights into disease mechanisms and potential therapeutic targets.The CTNNA3 Polyclonal Antibody is a reliable resource for investigating the functions and interactions of CTNNA3 in different biological contexts. Its utility in immunology, cell biology, and cancer research makes it an indispensable tool for advancing scientific knowledge and developing innovative treatments for various diseases.
Product Name:
CTNNA3 Rabbit Polyclonal Antibody
SKU:
CAB16519
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-240 of human CTNNA3 (NP_001278062.1).
This gene encodes a protein that belongs to the vinculin/alpha-catenin family. The encoded protein plays a role in cell-cell adhesion in muscle cells. Mutations in this gene are associated with arrhythmogenic right ventricular dysplasia, familial 13. Alternative splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
29119
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CTNNA3 Rabbit pAb (CAB16519) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 5s.
