The CTH Polyclonal Antibody (CAB6121) is a valuable tool for researchers studying CTH, an important enzyme involved in the metabolism of cysteine. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CTH protein, this antibody enables the detection and analysis of CTH in various cell types, making it ideal for studies in biochemistry and molecular biology.CTH, also known as cystathionine gamma-lyase, plays a crucial role in the transsulfuration pathway and the production of hydrogen sulfide, an important signaling molecule in the body.
Dysregulation of CTH has been implicated in various diseases, including cardiovascular disease, neurological disorders, and cancer. Understanding the function and regulation of CTH is essential for developing new treatments targeting the transsulfuration pathway and hydrogen sulfide signaling in these disease contexts.
Product Name:
Cystathionase/CTH Rabbit Polyclonal Antibody
SKU:
CAB6121
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-405 of human Cystathionase/Cystathionase/CTH (NP_001893.2).
This gene encodes a cytoplasmic enzyme in the trans-sulfuration pathway that converts cystathione derived from methionine into cysteine. Glutathione synthesis in the liver is dependent upon the availability of cysteine. Mutations in this gene cause cystathioninuria. Alternative splicing of this gene results in three transcript variants encoding different isoforms.
Purification Method:
Affinity purification
Gene ID:
1491
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Western blot analysis of various lysates, using Cystathionase/CTH Rabbit pAb (CAB6121) at 1:500 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
