The CTGF Polyclonal Antibody (PAC051454) is a valuable tool for researchers studying connective tissue growth factor (CTGF), a key protein involved in various cellular processes such as cell proliferation, differentiation, adhesion, and migration. This antibody, produced in rabbits, exhibits high specificity and sensitivity towards human samples, making it suitable for Western blot applications.CTGF is known for its role in promoting fibrosis, angiogenesis, and tissue repair, making it a target of interest in research areas such as wound healing, fibrosis-related diseases, and cancer progression. By targeting CTGF with this antibody, researchers can analyze its expression levels and localization in different cell types, providing valuable insights into its function and potential therapeutic applications.
Further understanding of CTGF and its regulatory mechanisms could lead to the development of novel treatments for diseases characterized by abnormal tissue remodeling and fibrosis, ultimately improving patient outcomes in various pathological conditions. Get your hands on the PAC051454 CTGF Polyclonal Antibody to enhance your research in the field of cell biology and disease pathogenesis.
Antibody Name:
Ctgf Antibody (PACO51454)
Antibody SKU:
PACO51454
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:200-1:2000
Species Reactivity:
Mouse, Rat
Immunogen:
Recombinant Mouse Connective tissue growth factor protein (26-344AA)
Western Blot. Positive WB detected in: Rat skeletal muscle tissue. All lanes: Ctgf antibody at 3µg/ml. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 38 kDa. Observed band size: 38 kDa..
Background:
Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes (By similarity). Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells (By similarity). Enhances fibroblast growth factor-induced DNA synthesis (By similarity).
Synonyms:
Connective tissue growth factor (CCN family member 2) (Hypertrophic chondrocyte-specific protein 24) (Protein FISP-12), Ctgf, Ccn2 Fisp-12 Fisp12 Hcs24
UniProt Protein Function:
CTGF: Major connective tissue mitoattractant secreted by vascular endothelial cells. Promotes proliferation and differentiation of chondrocytes. Mediates heparin- and divalent cation-dependent cell adhesion in many cell types including fibroblasts, myofibroblasts, endothelial and epithelial cells. Enhances fibroblast growth factor-induced DNA synthesis. Belongs to the CCN family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:
Protein type:Secreted, signal peptide; Secreted; Cell adhesion
