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CTGF Monoclonal Antibody [PAT18E7AT] (CPAB0086)

SKU:
CPAB0086
Product Type:
Antibody
Antibody Type:
Monoclonal Antibody
Reactivity:
Human
Host Species:
Mouse
Isotype:
IgG2a
Clone:
PAT18E7AT
Applications:
WB
ELISA
€149
Frequently bought together:

Description

system_update_alt Datasheet

CTGF Monoclonal Antibody [PAT18E7AT] (CPAB0086)

The CTGF (Connective Tissue Growth Factor) Polyclonal Antibody (CPAB0086) is a vital tool for researchers studying the role of CTGF in various biological processes. CTGF is a key factor in cell proliferation, migration, and adhesion, making it crucial in wound healing, fibrosis, and cancer progression.This antibody, produced in rabbits, is highly specific to human CTGF and has been validated for use in Western blot and immunohistochemistry applications. By binding to the CTGF protein, researchers can accurately detect and analyze CTGF expression in different cell types and tissues, providing valuable insights into its function and potential therapeutic targets.

CTGF is known to play a critical role in fibrotic diseases, such as pulmonary fibrosis and liver cirrhosis, as well as in promoting angiogenesis and tumor growth in cancer. Understanding the mechanisms by which CTGF functions is essential for developing targeted therapies to treat these conditions effectively. The CTGF Polyclonal Antibody is a valuable tool for unraveling the complexities of CTGF-related pathways and their implications in disease progression.

Product Name:CTGF Antibody
Product Sku:CPAB0086
Size:5μg
Host Species:Mouse
Immunogen:Anti-human CTGF mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human CTGF protein 27-349 amino acids purified from Ecoli.
Clone:PAT18E7AT.
Reactivity:Human
Applications:Western Blot, ELISA
Purification Method:CTGF antibody was purified by protein-A affinity chromatography.
Isotype:IgG2a
Background:Connective Tissue Growth Factor belongs to the CCN family of proteins. The CCN family presently consists of six members in human also known as: Cyr61 (Cystein rich 61), CTGF (Connective Tissue Growth Factor), Nov (Nephroblastoma Overexpressed gene), WISP-1, 2 and 3 (Wnt-1 Induced Secreted Proteins). The CCN genes encode secreted proteins associated with the Extracellular Matrix (ECM) and cell membrane. CCN proteins are matricellular proteins which are involved in the regulation of various cellular functions including: proliferation, differentiation, survival, adhesion and migration. They are expressed in derivatives of the three embryonic sheets and are implicated in the development of kidney, nervous system, muscle, bone marrow, cartilage and bone. During adulthood, they are implicated in wound healing, bone fracture repair, and pathologies such as: fibrosis, vascular ailments and tumorigenesis.
Synonyms:CCN2, NOV2, HCS24, IGFBP8, MGC102839, CTGF, Connective Tissue Growth Factor.
Storage Buffer:For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles.

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