The CTBP2 Polyclonal Antibody (CAB16826) is a valuable tool for research involving the CTBP2 protein, which plays a key role in gene regulation and cellular processes. This antibody, raised in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CTBP2 protein, this antibody allows for the detection and analysis of CTBP2 expression in various cell types, making it an essential reagent for studies in molecular biology and cancer research.CTBP2, also known as C-terminal binding protein 2, is a transcriptional corepressor that plays a crucial role in regulating gene expression and cellular proliferation.
Dysregulation of CTBP2 has been implicated in various disease states, including cancer and neurological disorders. Therefore, understanding the function of CTBP2 is essential for uncovering its potential role in disease pathology and for developing targeted therapies.Overall, the CTBP2 Polyclonal Antibody (CAB16826) offers researchers a reliable tool for investigating the role of CTBP2 in various biological processes and diseases, ultimately leading to a deeper understanding of its function and potential therapeutic applications.
Product Name:
CTBP2 Rabbit Polyclonal Antibody
SKU:
CAB16826
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 300 to the C-terminus of human CTBP2 (NP_001320.1).
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1488
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of various lysates using CTBP2 Rabbit pAb (CAB16826) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
