CTBP2 Rabbit Polyclonal Antibody (CAB2257)
- SKU:
- CAB2257
- Product Type:
- Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | CTBP2 Rabbit Polyclonal Antibody |
SKU: | CAB2257 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 345-445 of human CTBP2 (NP_001320.1). |
Sequence: | ITGR IPES LRNC VNKE FFVT SAPW SVID QQAI HPEL NGAT YRYP PGIV GVAP GGLP AAME GIIP GGIP VTHN LPTV AHPS QAPS PNQP TKHG DNRE HPNE Q |
Tested Applications: | WB IF/ICC ELISA |
Recommended Dilution: | WB,1:500 - 1:2000 IF/ICC,1:50 - 1:200 |
Synonyms: | CTBP2 |
Positive Sample: | U-251MG,HeLa,BxPC-3,Mouse brain,Rat brain |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Nucleus, synapse. |
Calculated MW: | 49kDa |
Observed MW: | 47kDa |
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1488 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3. |