CTBP2 Rabbit Monoclonal Antibody (CAB0463)
- SKU:
- CAB0463
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Mouse
- Rat
- Host Species:
- Rabbit
- Isotype:
- IgG
- Synonyms:
- CTBP2
- C-terminal-binding protein 2
- Research Area:
- Developmental Biology
Frequently bought together:
Description
Product Name: | CTBP2 Rabbit Monoclonal Antibody |
SKU: | CAB0463 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human,Mouse,Rat |
Immunogen: | A synthetic peptide corresponding to a sequence within amino acids 346-445 of human CTBP2 (P56545). |
Sequence: | TGRI PESL RNCV NKEF FVTS APWS VIDQ QAIH PELN GATY RYPP GIVG VAPG GLPA AMEG IIPG GIPV THNL PTVA HPSQ APSP NQPT KHGD NREH PNEQ |
Tested Applications: | WB IHC-P IF/ICC IP ELISA |
Recommended Dilution: | WB,1:500 - 1:1000 IHC-P,1:50 - 1:200 IF/ICC,1:50 - 1:200 IP,0.5μg-4μg antibody for 200μg-400μg extracts of whole cells |
Synonyms: | CTBP2; C-terminal-binding protein 2 |
Positive Sample: | HeLa,NIH/3T3,Rat testis |
Conjugate: | Unconjugated |
Cellular Localization: | Cell junction, Nucleus, synapse. |
Calculated MW: | 49kDa |
Observed MW: | 47kDa |
This gene produces alternative transcripts encoding two distinct proteins. One protein is a transcriptional repressor, while the other isoform is a major component of specialized synapses known as synaptic ribbons. Both proteins contain a NAD+ binding domain similar to NAD+-dependent 2-hydroxyacid dehydrogenases. A portion of the 3' untranslated region was used to map this gene to chromosome 21q21.3; however, it was noted that similar loci elsewhere in the genome are likely. Blast analysis shows that this gene is present on chromosome 10. Several transcript variants encoding two different isoforms have been found for this gene.
Purification Method: | Affinity purification |
Gene ID: | 1488 |
Clone Number: | ARC2509 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,0.05% BSA,50% glycerol,pH7.3. |