The CTBP1 Polyclonal Antibody (CAB3257) is a valuable tool for researchers studying CTBP1, a transcriptional corepressor involved in various cellular processes, including the regulation of gene expression and cell proliferation. This antibody, generated in rabbits, shows strong reactivity with human samples and has been validated for use in Western blotting applications.CTBP1, also known as C-terminal binding protein 1, is a crucial player in multiple signaling pathways that control cell growth and differentiation. By targeting CTBP1, researchers can gain insight into its role in cancer development, metabolic regulation, and other disease processes.
The ability to detect and analyze CTBP1 protein levels in different cell types makes this antibody suitable for investigations in oncology, developmental biology, and beyond.The CTBP1 Polyclonal Antibody (CAB3257) offers a reliable tool for researchers seeking to unravel the complex functions of CTBP1 in health and disease. Its specificity and sensitivity make it a valuable asset for research projects aiming to illuminate the molecular mechanisms underlying cellular processes regulated by CTBP1.
Product Name:
CtBP1 Rabbit Polyclonal Antibody
SKU:
CAB3257
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-250 of human CtBP1 (NP_001319.1).
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1487
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of lysates from HeLa cells, using CtBP1 Rabbit pAb (CAB3257).Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.