The CTBP1 Polyclonal Antibody (CAB1707) is a valuable tool for researchers studying CTBP1, a protein involved in various cellular functions, including transcriptional repression and apoptosis. This antibody, generated in rabbits, has been rigorously validated for use in Western blot applications and is highly reactive with human samples.CTBP1, also known as C-terminal binding protein 1, is a transcriptional co-repressor that plays a critical role in regulating gene expression and cell growth. Dysregulation of CTBP1 has been implicated in various diseases, including cancer, making it a promising target for therapeutic interventions.
By specifically binding to CTBP1, this polyclonal antibody enables researchers to detect and analyze the protein in different cell types, providing insights into its biological functions and potential clinical relevance. Its use in immunology and cancer research makes it an essential tool for understanding the role of CTBP1 in disease pathogenesis and developing targeted treatments.
Product Name:
CtBP1 Rabbit Polyclonal Antibody
SKU:
CAB1707
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 20-250 of human CtBP1 (NP_001319.1).
This gene encodes a protein that binds to the C-terminus of adenovirus E1A proteins. This phosphoprotein is a transcriptional repressor and may play a role during cellular proliferation. This protein and the product of a second closely related gene, CTBP2, can dimerize. Both proteins can also interact with a polycomb group protein complex which participates in regulation of gene expression during development. Alternative splicing of transcripts from this gene results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1487
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of lysates from mouse brain, using CtBP1 Rabbit pAb (CAB1707) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).
