The CTAGE5 Antibody (PACO16081) is a highly specific polyclonal antibody designed for research involving CTAGE5, a protein involved in cellular transport and immune regulation. This antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for use in various applications, including Western blotting and immunohistochemistry.CTAGE5 is known to play a pivotal role in intracellular vesicle transport, as well as in modulating immune responses by interacting with immune cells and regulating cytokine production. Its involvement in these important cellular processes makes it a valuable target for researchers studying immune function, inflammation, and autoimmune diseases.
By utilizing the CTAGE5 Antibody, researchers can detect and analyze the presence of CTAGE5 protein in various cell types and tissue samples, providing valuable insights into its function and potential therapeutic implications. This antibody is an essential tool for studies in immunology, cancer research, and molecular biology, helping to advance our understanding of immune regulation and cellular transport mechanisms.
The image on the left is immunohistochemistry of paraffin-embedded Human brain tissue using PACO16081(CTAGE5 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Gel: 10%SDS-PAGE, Lysate: 40 μg, Lane 1-3: PC3 cells, human brain malignant glioma tissue, A172 cells, Primary antibody: PACO16081(CTAGE5 Antibody) at dilution 1/200, Secondary antibody: Goat anti rabbit IgG at 1/8000 dilution, Exposure time: 1 second.
The image on the left is immunohistochemistry of paraffin-embedded Human thyroid cancer tissue using PACO16081(CTAGE5 Antibody) at dilution 1/40, on the right is treated with fusion protein. (Original magnification: x200).
Background:
The protein encoded by this gene is a tumor-associated antigen found in cutaneous T-cell lymphoma and several other cancers. Autoantibodies against the encoded protein have been found in some cancers. Several transcript variants encoding different isoforms have been found for this gene.
Synonyms:
CTAGE family, member 5
UniProt Protein Function:
CTAGE5: Tumor-associated antigen. Autoantibodies against CTAGE5 are present in several cancer types, including benign meningioma and cutaneous T-cell lymphoma (CTCL). Belongs to the cTAGE family. 8 isoforms of the human protein are produced by alternative splicing.Protein type: Cancer Testis Antigen (CTA); Membrane protein, integralChromosomal Location of Human Ortholog: 14q13.3Cellular Component: endoplasmic reticulum membrane; membraneMolecular Function: enzyme activator activity; protein bindingBiological Process: ER to Golgi vesicle-mediated transport
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a tumor-associated antigen found in cutaneous T-cell lymphoma and several other cancers. Autoantibodies against the encoded protein have been found in some cancers. Several transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Oct 2011]
