The CSTL1 Antibody (PACO03439) is a polyclonal antibody designed for research involving the cysteine protease, CSTL1. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in Western blot applications. It binds to the CSTL1 protein, allowing for detection and analysis in a variety of cell types, making it ideal for studies in the fields of cell biology and cancer research.CSTL1, also known as cathepsin L1, is a key player in cell remodeling and tissue regeneration. It is involved in the breakdown of proteins and peptides within lysosomes, contributing to various cellular processes such as apoptosis and autophagy.
The expression of CSTL1 has been linked to cancer progression and metastasis, making it a promising target for therapeutic interventions.By utilizing the CSTL1 Antibody in your research, you can gain valuable insights into the role of CSTL1 in cellular processes and its potential implications in disease development. Understanding the function of CSTL1 could pave the way for innovative treatments for cancer and other related disorders.
Antibody Name:
CSTL1 Antibody
Antibody SKU:
PACO03439
Size:
50ug
Host Species:
Rabbit
Tested Applications:
ELISA, IF
Recommended Dilutions:
IF:1:200-1:1000
Species Reactivity:
Human
Immunogen:
synthesized peptide derived from the Internal region of human Cystatin L1.
Form:
Liquid
Storage Buffer:
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:
The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:
Polyclonal
Isotype:
IgG
Conjugate:
Non-conjugated
Synonyms:
CSTL1; Cystatin-like 1; RCET11
UniProt Protein Function:
CSTL1: The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located at the telomeric end of the cystatin locus and encodes a type 2 cystatin-like protein. The specific function of this protein has not been determined. [provided by RefSeq, Jul 2008]Protein type: Secreted; Secreted, signal peptideChromosomal Location of Human Ortholog: 20p11.21Cellular Component: extracellular regionMolecular Function: cysteine protease inhibitor activity
UniProt Protein Details:
NCBI Summary:
The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located at the telomeric end of the cystatin locus and encodes a type 2 cystatin-like protein. The specific function of this protein has not been determined. [provided by RefSeq, Jul 2008]
