The CSTF2 Polyclonal Antibody (CAB8116) is a valuable tool for researchers studying CSTF2, a protein involved in mRNA processing and gene expression regulation. This antibody, produced in rabbits, is highly specific to human CSTF2 and has been validated for use in Western blot applications. By binding to the CSTF2 protein, the antibody enables accurate detection and analysis in various cellular contexts, making it an ideal choice for studies in molecular biology and gene regulation mechanisms.CSTF2, also known as Cleavage Stimulation Factor Subunit 2, plays a crucial role in mRNA polyadenylation, a key step in mRNA maturation and stability.
Dysregulation of CSTF2 has been linked to various human diseases, including cancer and neurological disorders, highlighting its importance as a potential therapeutic target. Investigating the functions and interactions of CSTF2 is essential for advancing our understanding of gene expression regulation and developing targeted interventions for related pathologies.
Product Name:
CSTF2 Rabbit Polyclonal Antibody
SKU:
CAB8116
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-180 of human CSTF2 (NP_001316.1).
This gene encodes a nuclear protein with an RRM (RNA recognition motif) domain. The protein is a member of the cleavage stimulation factor (CSTF) complex that is involved in the 3' end cleavage and polyadenylation of pre-mRNAs. Specifically, this protein binds GU-rich elements within the 3'-untranslated region of mRNAs.
Purification Method:
Affinity purification
Gene ID:
1478
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CSTF2 Rabbit pAb (CAB8116) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 20s.
