The CSTF1 Polyclonal Antibody (CAB5915) is a valuable tool for researchers studying CSTF1, a protein involved in mRNA processing and gene regulation. This antibody, generated in rabbits, is highly specific for human samples and has been validated for use in Western blot applications. By targeting the CSTF1 protein, researchers can investigate its role in various cellular processes, providing insights into gene expression and potential therapeutic targets in diseases like cancer and developmental disorders.
CSTF1, also known as Cleavage Stimulation Factor Subunit 1, plays a crucial role in polyadenylation of mRNA, a process essential for mRNA stability and translation. Dysregulation of CSTF1 has been implicated in various diseases, making it a promising target for drug discovery and therapeutic interventions. By studying CSTF1 using this antibody, researchers can uncover its molecular mechanisms and potential implications in disease progression, paving the way for new treatment strategies.
Product Name:
CSTF1 Rabbit Polyclonal Antibody
SKU:
CAB5915
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-220 of human CSTF1 (NP_001315.1).
This gene encodes one of three subunits which combine to form cleavage stimulation factor (CSTF). CSTF is involved in the polyadenylation and 3'end cleavage of pre-mRNAs. Similar to mammalian G protein beta subunits, this protein contains transducin-like repeats. Several transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1477
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CSTF1 antibody (CAB5915) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 1s.
