The CSRP3 Polyclonal Antibody (CAB6569) is a valuable tool for researchers studying CSRP3, a protein involved in regulating muscle cell function and development. This antibody, generated in rabbits, shows high reactivity with human samples and is validated for use in applications such as Western blotting. By binding specifically to the CSRP3 protein, this antibody allows for the detection and analysis of CSRP3 expression in various cell types, making it a useful tool for investigating muscle-related diseases and conditions.CSRP3, also known as muscle LIM protein, is a key regulator of muscle cell differentiation and function.
Its role in maintaining muscle integrity and function makes it a potential target for research in muscle-related disorders such as muscular dystrophy and heart failure. Understanding the function and regulation of CSRP3 is essential for developing therapies aimed at treating these conditions and improving muscle health.Overall, the CSRP3 Polyclonal Antibody is a valuable resource for researchers interested in exploring the role of CSRP3 in muscle biology and its potential implications for human health and disease.
Product Name:
CSRP3 Rabbit Polyclonal Antibody
SKU:
CAB6569
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human CSRP3 (NP_003467.1).
Cytoplasm, Nucleus, Z line, cytoskeleton, myofibril, sarcomere.
Calculated MW:
21kDa
Observed MW:
25kDa
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8048
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CSRP3 Rabbit pAb (CAB6569) at 1:1000 dilution._Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution._Lysates/proteins: 25μg per lane._Blocking buffer: 3% nonfat dry milk in TBST._Detection: ECL Enhanced Kit (AbGn00021)._Exposure time: 90s.
