The CSRP3 Polyclonal Antibody (CAB13372) is a valuable tool for studying CSRP3, a protein involved in muscle cell structure and function. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in various applications, including Western blotting. By binding to the CSRP3 protein, researchers can accurately detect and analyze its expression in different cell types, making it an essential tool for studies in muscle biology and disease research.CSRP3, also known as muscle LIM protein, plays a crucial role in maintaining the structure and function of muscle cells, making it a key player in muscle development and function.
Dysregulation of CSRP3 has been linked to various muscle disorders and cardiac diseases, highlighting the importance of understanding its role in muscle physiology. By studying the activity of CSRP3, researchers can uncover potential therapeutic targets for treating muscle-related conditions and improving overall muscle health.
Product Name:
CSRP3 Rabbit Polyclonal Antibody
SKU:
CAB13372
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 1-194 of human CSRP3 (NP_003467.1).
Cytoplasm, Nucleus, Z line, cytoskeleton, myofibril, sarcomere.
Calculated MW:
21kDa
This gene encodes a member of the CSRP family of LIM domain proteins, which may be involved in regulatory processes important for development and cellular differentiation. The LIM/double zinc-finger motif found in this protein is found in a group of proteins with critical functions in gene regulation, cell growth, and somatic differentiation. Mutations in this gene are thought to cause heritable forms of hypertrophic cardiomyopathy (HCM) and dilated cardiomyopathy (DCM) in humans. Alternatively spliced transcript variants with different 5' UTR, but encoding the same protein, have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
8048
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Immunofluorescence analysis of HeLa cells using CSRP3 antibody (CAB13372). Blue: DAPI for nuclear staining.
