The CSRP3 Polyclonal Antibody (PAC063479) is a valuable tool for researchers studying CSRP3, a protein associated with muscle development and function. This antibody, generated in rabbits, exhibits high specificity for human samples and has been validated for use in Western blot applications. By targeting the CSRP3 protein, this antibody allows for accurate detection and analysis in a variety of cell types, making it ideal for research in cardiology, muscle biology, and related fields.CSRP3, also known as cardiac LIM domain protein, plays a crucial role in maintaining the structural integrity and contractile function of cardiac muscle.
Dysregulation of CSRP3 has been linked to various cardiovascular diseases, making it a promising target for therapeutic interventions aimed at improving heart health. By understanding the function of CSRP3, researchers can gain insights into the mechanisms underlying heart disease and potentially develop novel treatment strategies to combat these conditions.
Antibody Name:
CSRNP3 Antibody (PACO63479)
Antibody SKU:
PACO63479
Size:
50ul
Host Species:
Rabbit
Tested Applications:
ELISA, WB
Recommended Dilutions:
ELISA:1:2000-1:10000, WB:1:1000-1:5000
Species Reactivity:
Human
Immunogen:
Peptide sequence from Human Cysteine/serine-rich nuclear protein 3 protein (518-536AA)
Western Blot. Positive WB detected in: SH-SY5Y whole cell lysate, U251 whole cell lysate. All lanes: CSRNP3 antibody at 1:2000. Secondary. Goat polyclonal to rabbit IgG at 1/50000 dilution. Predicted band size: 65, 59 kDa. Observed band size: 65 kDa.
Background:
Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. Plays a role in apoptosis (By similarity).
Synonyms:
Cysteine/serine-rich nuclear protein 3 (CSRNP-3) (Protein FAM130A2) (TGF-beta-induced apoptosis protein 2) (TAIP-2), CSRNP3, FAM130A2 TAIP2
UniProt Protein Function:
FAM130A2: Binds to the consensus sequence 5'-AGAGTG-3' and has transcriptional activator activity. Plays a role in apoptosis. Belongs to the AXUD1 family. 2 isoforms of the human protein are produced by alternative splicing.Chromosomal Location of Human Ortholog: 2q24.3Cellular Component: nucleusMolecular Function: transcription factor activityBiological Process: positive regulation of apoptosis; positive regulation of transcription from RNA polymerase II promoter
