The CSNK2B Polyclonal Antibody (CAB17467) is a valuable tool for research involving CSNK2B, a protein involved in various cellular processes including cell growth, differentiation, and proliferation. This antibody, generated in rabbits, is highly specific to human samples and has been validated for use in Western blot applications. By binding to the CSNK2B protein, this antibody enables accurate detection and analysis in different cell types, making it an essential component for studies in molecular biology and cancer research.
CSNK2B, also known as casein kinase 2 beta subunit, is an important regulator of cell signaling pathways and has been implicated in various diseases, including cancer and neurodegenerative disorders. Its role in mediating cellular responses to external stimuli and promoting cell survival makes it a promising target for therapeutic interventions. Investigating the function of CSNK2B is critical for developing strategies to manipulate its activity for potential therapeutic benefits in disease treatment and management.
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1460
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using Casein Kinase 2 beta (Casein Kinase 2 beta (CSNK2B)) Rabbit pAb (CAB17467) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
