The CSNK2B Polyclonal Antibody (CAB14722) is designed for research involving CSNK2B, a protein kinase that plays a key role in various cellular processes, including cell growth, cell division, and cell survival. This antibody, produced in rabbits, is highly specific for human samples and is validated for use in Western blot applications. It binds to the CSNK2B protein, enabling efficient detection and analysis in different cell types, making it ideal for studies in molecular biology and cancer research.CSNK2B, also known as casein kinase 2 subunit beta, is a regulatory subunit of the protein kinase CK2, which is involved in diverse signaling pathways and cellular functions.
Dysregulation of CK2 activity has been implicated in various diseases, including cancer, neurodegenerative disorders, and cardiovascular diseases. Investigating the role of CSNK2B in these conditions can provide valuable insights into disease mechanisms and potential therapeutic targets.The CSNK2B Polyclonal Antibody offers researchers a reliable tool for studying the expression and function of CSNK2B in different biological contexts. By elucidating the molecular mechanisms regulated by CSNK2B, researchers can advance our understanding of disease processes and identify new strategies for targeted interventions.
Recombinant fusion protein containing a sequence corresponding to amino acids 1-215 of human Casein Kinase 2 beta (Casein Kinase 2 beta (CSNK2B)) (NP_001311.3).
This gene encodes the beta subunit of casein kinase II, a ubiquitous protein kinase which regulates metabolic pathways, signal transduction, transcription, translation, and replication. The enzyme is composed of three subunits, alpha, alpha prime and beta, which form a tetrameric holoenzyme. The alpha and alpha prime subunits are catalytic, while the beta subunit serves regulatory functions. The enzyme localizes to the endoplasmic reticulum and the Golgi apparatus. Two transcript variants encoding different isoforms have been found for this gene.
Purification Method:
Affinity purification
Gene ID:
1460
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using Casein Kinase 2 beta (Casein Kinase 2 beta (CSNK2B)) Rabbit pAb (CAB14722) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 30s.
