The CSNK1G1 Polyclonal Antibody (CAB7510) is a powerful tool for research involving CSNK1G1, a protein kinase involved in various cellular processes, including cell cycle regulation and circadian rhythm. This antibody is raised in rabbits and is highly reactive with human samples, making it suitable for Western blot applications. CSNK1G1, also known as casein kinase 1 gamma 1, has been implicated in the regulation of Wnt signaling and the modulation of various physiological processes. By targeting the CSNK1G1 protein, this antibody allows for the detection and analysis of CSNK1G1 in different cell types, making it ideal for studies in cell biology and molecular signaling pathways.
The role of CSNK1G1 in cellular signaling and its potential involvement in diseases such as cancer and neurological disorders makes it a promising target for further research. By understanding the function of CSNK1G1, researchers can uncover valuable insights into the mechanisms underlying these diseases and potentially develop targeted therapies.
Product Name:
CSNK1G1 Rabbit Polyclonal Antibody
SKU:
CAB7510
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 298-422 of human CSNK1G1 (NP_071331.2).
This gene encodes a member of the casein kinase I gene family. This family is comprised of serine/threonine kinases that phosphorylate acidic proteins such as caseins. The encoded kinase plays a role in cell cycle checkpoint arrest in response to stalled replication forks by phosphorylating Claspin. A mutation in this gene may be associated with non-syndromic early-onset epilepsy (NSEOE).
Purification Method:
Affinity purification
Gene ID:
53944
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CSNK1G1 antibody (CAB7510) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
