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CSNK1G1/CSNK1G2/CSNK1G3 Antibody (PACO04624)

SKU:
PACO04624
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€269
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Description

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CSNK1G1/CSNK1G2/CSNK1G3 Antibody (PACO04624)

The CSNK1G1, CSNK1G3, CSNK1G2 Polyclonal Antibody (PACO04624) is a versatile tool for research applications involving these important protein kinases. Raised in rabbits, this antibody is highly specific and sensitive for detecting the CSNK1G1, CSNK1G3, and CSNK1G2 proteins in human samples. Validated for use in Western blotting, immunohistochemistry, and immunofluorescence, this antibody enables accurate analysis of the expression and localization of these kinases in various cell types.CSNK1G1, CSNK1G3, and CSNK1G2 are members of the casein kinase 1 family, playing crucial roles in various signaling pathways involved in cell growth, differentiation, and circadian rhythm regulation.

Dysregulation of these kinases has been implicated in diseases such as cancer, neurodegenerative disorders, and metabolic diseases, making them attractive targets for therapeutic interventions. By using this polyclonal antibody, researchers can gain insights into the functions and dysregulation of CSNK1G1, CSNK1G3, and CSNK1G2, advancing our understanding of pathophysiological mechanisms and potentially leading to the development of novel treatment strategies.

Antibody Name:CSNK1G1/CSNK1G2/CSNK1G3 Antibody
Antibody SKU:PACO04624
Size:50ug
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:IHC:1:100-1:300
Species Reactivity:Human, Mouse, Rat
Immunogen:synthesized peptide derived from human Casein Kinase Igamma1/2/3 around the non-phosphorylation site of Y263.
Form:Liquid
Storage Buffer:Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:CSNK1G1; Casein kinase I isoform gamma-1; CKI-gamma 1; CSNK1G2; CK1G2; Casein kinase I isoform gamma-2; CKI-gamma 2; CSNK1G3; Casein kinase I isoform gamma-3; CKI-gamma 3
UniProt Protein Function:CK1G1: an ubiquitous protein kinase of the CK1 family. Involved in growth and morphogenesis. Two splice variant isoforms have been described.
UniProt Protein Details:

Protein type:EC 2.7.11.1; Protein kinase, Ser/Thr (non-receptor); Kinase, protein; Protein kinase, CK1; CK1 group; CK1 family

Chromosomal Location of Human Ortholog: 15q22.1-q22.31

Cellular Component: cytoplasm; nucleus

Molecular Function:protein serine/threonine kinase activity; ATP binding

Biological Process: regulation of cell shape; peptidyl-serine phosphorylation; Wnt receptor signaling pathway; endocytosis

NCBI Summary:This gene encodes a member of the casein kinase I gene family. The encoded protein is a serine/threonine kinase that phosphorylates acidic proteins, and participates in pathways for cell growth. [provided by RefSeq, Nov 2011]
UniProt Code:Q9HCP0
NCBI GenInfo Identifier:18202957
NCBI Gene ID:53944
NCBI Accession:Q9HCP0.1
UniProt Secondary Accession:Q9HCP0,Q5JPH1, Q96AE9, Q9HCP1,
UniProt Related Accession:Q9HCP0
Molecular Weight:422
NCBI Full Name:Casein kinase I isoform gamma-1
NCBI Synonym Full Names:casein kinase 1, gamma 1
NCBI Official Symbol:CSNK1G1  
NCBI Official Synonym Symbols:CK1gamma1  
NCBI Protein Information:casein kinase I isoform gamma-1; CKI-gamma 1
UniProt Protein Name:Casein kinase I isoform gamma-1
Protein Family:Casein kinase
UniProt Gene Name:CSNK1G1  
UniProt Entry Name:KC1G1_HUMAN

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