CSNK1A1 Monoclonal Antibody [PAT2E2AT] (CPAB0163)
- SKU:
- CPAB0163
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT2E2AT
- Applications:
- WB
- ELISA
Description
CSNK1A1 Monoclonal Antibody [PAT2E2AT] (CPAB0163)
The CSNK1A1 Polyclonal Antibody (CPAB0163) is specifically designed for research involving CSNK1A1, a protein kinase known for its role in various cellular processes such as cell cycle progression, DNA damage response, and circadian rhythm regulation. This antibody is raised in rabbits and exhibits high reactivity with human samples, making it an excellent tool for Western blot applications.CSNK1A1, also known as casein kinase 1 alpha 1, is a key player in regulating important signaling pathways involved in cell growth, proliferation, and differentiation. By targeting this protein with the CPAB0163 antibody, researchers can detect and study CSNK1A1 in different cell types, providing valuable insights into its functions and potential implications in diseases such as cancer, neurological disorders, and circadian rhythm disorders.
Understanding the role of CSNK1A1 in cellular processes holds promising opportunities for developing targeted therapies and interventions for various diseases. The CPAB0163 antibody offers researchers a reliable and specific tool for investigating the functions and mechanisms of CSNK1A1, ultimately advancing our knowledge in the field of cell biology and potential therapeutic strategies.
Product Name: | CSNK1A1 Antibody |
Product Sku: | CPAB0163 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human CSNK1A1 mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CSNK1A1 amino acids 1-337 purified from Ecoli. |
Clone: | PAT2E2AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | CSNK1A1 antibody was purified from mouse ascitic fluids by protein-G affinity chromatography. |
Isotype: | IgG2b |
Background: | Caseine Kinase 1 alpha belongs is a member of the protein kinase superfamily, CK1 Ser/Thr protein kinase family, Casein kinase I subfamily. The CK1 isoforms - alpha, beta, gamma, delta, epsilon and their splice variants are involved in diverse cellular processes including membrane trafficking, circadian rhythm, cell cycle progression, chromosome segregation, apoptosis and cellular differentiation. Possibly CSNK1A1 can phosphorylate a large number of proteins and is involved in Wnt signaling where it phosphorylates CTNNB1 on Ser45. CSNK1A1 also interacts with the Axin complex. |
Synonyms: | Casein kinase I isoform alpha, CKI-alpha, CK1, CSNK1A1, HLCDGP1, PRO2975. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |