CSK Monoclonal Antibody [PAT7C6AT] (CPAB0258)
- SKU:
- CPAB0258
- Product Type:
- Antibody
- Antibody Type:
- Monoclonal Antibody
- Reactivity:
- Human
- Host Species:
- Mouse
- Isotype:
- IgG2b
- Clone:
- PAT7C6AT
- Applications:
- WB
- ELISA
Description
CSK Monoclonal Antibody [PAT7C6AT] (CPAB0258)
The CSK Polyclonal Antibody (CPAB0258) is a valuable tool for researchers studying CSK, a non-receptor tyrosine kinase involved in signal transduction and cell communication. This antibody, produced in rabbits, exhibits high reactivity with human samples and is validated for Western blot applications. By specifically targeting the CSK protein, this antibody enables accurate detection and analysis in a variety of cell types, making it ideal for investigations in cell signaling, cancer research, and developmental biology.CSK, or C-terminal Src kinase, plays a crucial role in regulating the activity of Src family kinases, which are involved in cell growth, differentiation, and survival.
Dysregulation of CSK activity has been implicated in various diseases, including cancer and autoimmune disorders, highlighting the importance of understanding its function in cellular processes. The CSK Polyclonal Antibody provides researchers with a powerful tool to explore the role of CSK in these contexts and potentially identify novel therapeutic targets for disease intervention.
Product Name: | CSK Antibody |
Product Sku: | CPAB0258 |
Size: | 5μg |
Host Species: | Mouse |
Immunogen: | Anti-human CSK mAb, is derived from hybridization of mouse F myeloma cells with spleen cells from BALB/c mice immunized with recombinant human CSK amino acids 1-45 purified from Ecoli. |
Clone: | PAT7C6AT. |
Reactivity: | Human |
Applications: | Western Blot, ELISA |
Purification Method: | CSK antibody was purified from mouse ascitic fluids by protein-A affinity chromatography. |
Isotype: | IgG2b |
Background: | C-Src Tyrosine Kinase, also known as CSK, regulates cell growth, migration, differentiation, and immune response. CSK Phosphorylates tyrosine residues located in the C-terminal tails of Src-family kinases. CSK is a protein coding gene which suppresses signaling by several surface receptors. Among CSK's related pathways are PI-3K cascade and Signaling by FGFR. |
Synonyms: | Tyrosine-protein kinase CSK, C-Src kinase, Protein-tyrosine kinase CYL, CSK, C-Src Tyrosine Kinase. |
Storage Buffer: | For periods up to 1 month store at 4°C, for longer periods of time, store at -20°C. Prevent freeze thaw cycles. |