The CSH2 Polyclonal Antibody (PACO08628) is a vital tool for researchers studying the CSH2 protein, which plays a key role in immune regulation and response. This antibody, produced in rabbits, is highly specific to human samples and has been validated for Western blot applications. By binding to the CSH2 protein, researchers can easily detect and analyze its expression in a variety of cell types, making it an ideal choice for studies in immunology and cancer research.CSH2, also known as a crucial signaling molecule in immune regulation, is involved in modulating immune responses and inflammatory processes. Its role in immune regulation makes it a promising target for research into diseases such as cancer, autoimmune disorders, and chronic inflammatory conditions.
Understanding the function of CSH2 is essential for the development of potential therapies that aim to manipulate immune responses in different disease settings.Invest in the CSH2 Polyclonal Antibody (PACO08628) for reliable and accurate detection of CSH2 protein levels in your research. With its high specificity and validation for Western blot applications, this antibody is a valuable asset for scientists investigating immune regulation and related diseases.
CSH1: Produced only during pregnancy and is involved in stimulating lactation, fetal growth and metabolism. Does not interact with GHR but only activates PRLR through zinc-induced dimerization. Belongs to the somatotropin/prolactin family.Protein type: Secreted, signal peptide; SecretedChromosomal Location of Human Ortholog: 17q24.2Cellular Component: extracellular regionMolecular Function: metal ion binding; hormone activity
UniProt Protein Details:
NCBI Summary:
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, while the ratio of 1 to 2 increases by term. Structural and expression differences provide avenues for developmental regulation and tissue specificity. [provided by RefSeq, Jul 2008]
