Placental lactogen (CSH1) Rabbit Polyclonal Antibody (CAB1972)
- SKU:
- CAB1972
- Product Type:
- Antibody
- Reactivity:
- Human
- Host Species:
- Rabbit
- Isotype:
- IgG
- Research Area:
- Signal Transduction
Description
Product Name: | Placental lactogen (CSH1) Rabbit Polyclonal Antibody |
SKU: | CAB1972 |
Size: | 20uL, 100uL |
Isotype: | IgG |
Host Species: | Rabbit |
Reactivity: | Human |
Immunogen: | Recombinant fusion protein containing a sequence corresponding to amino acids 27-217 of human Placental lactogen (Placental lactogen (CSH1)) (NP_001308.1). |
Sequence: | VQTV PLSR LFDH AMLQ AHRA HQLA IDTY QEFE ETYI PKDQ KYSF LHDS QTSF CFSD SIPT PSNM EETQ QKSN LELL RISL LLIE SWLE PVRF LRSM FANN LVYD TSDS DDYH LLKD LEEG IQTL MGRL EDGS RRTG QILK QTYS KFDT NSHN HDAL LKNY GLLY CFRK DMDK VETF LRMV QCRS VEGS CGF |
Tested Applications: | IHC-P ELISA |
Recommended Dilution: | IHC-P,1:50 - 1:100 |
Synonyms: | PL; CSA; CS-1; CSMT; GHB3; hCS-1; hCS-A; Placental lactogen (CSH1) |
Conjugate: | Unconjugated |
Cellular Localization: | endoplasmic reticulum, endosome lumen, extracellular region, extracellular space |
Calculated MW: | 25kDa |
The protein encoded by this gene is a member of the somatotropin/prolactin family of hormones and plays an important role in growth control. The gene is located at the growth hormone locus on chromosome 17 along with four other related genes in the same transcriptional orientation; an arrangement which is thought to have evolved by a series of gene duplications. Although the five genes share a remarkably high degree of sequence identity, they are expressed selectively in different tissues. Alternative splicing generates additional isoforms of each of the five growth hormones, leading to further diversity and potential for specialization. This particular family member is expressed mainly in the placenta and utilizes multiple transcription initiation sites. Expression of the identical mature proteins for chorionic somatomammotropin hormones 1 and 2 is upregulated during development, although the ratio of 1 to 2 increases by term. Mutations in this gene result in placental lactogen deficiency and Silver-Russell syndrome.
Purification Method: | Affinity purification |
Gene ID: | 1442 |
Storage Buffer: | Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3. |