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CSGALNACT2 Antibody (PACO08626)

SKU:
PACO08626
Product Type:
Antibody
Reactivity:
Human
Mouse
Rat
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
WB
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€459
Frequently bought together:

Description

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CSGALNACT2 Antibody (PACO08626)

The CSGLNACT2 Polyclonal Antibody (PACO08626) is a valuable tool for researchers studying CSGLNACT2, a key enzyme involved in glycosaminoglycan biosynthesis. This antibody, produced in rabbits, is highly specific for CSGLNACT2 in human samples and is validated for use in a variety of applications, including Western blotting. By binding to the CSGLNACT2 protein, this antibody enables accurate detection and analysis in different cell types, making it essential for studies in glycobiology and related fields.CSGLNACT2 plays a crucial role in the biosynthesis of glycosaminoglycans, critical components of the extracellular matrix and important in various biological processes.

Research into CSGLNACT2 is vital for understanding the mechanisms of glycosaminoglycan synthesis and its implications in health and disease. This antibody aids in elucidating the function of CSGLNACT2, making it a valuable tool for investigations into conditions such as cancer, developmental disorders, and inflammatory diseases where glycosaminoglycan metabolism is dysregulated.

Antibody Name:CSGALNACT2 Antibody (PACO08626)
Antibody SKU:PACO08626
Size:50ul
Host Species:Rabbit
Tested Applications:ELISA, WB
Recommended Dilutions:
Species Reactivity:Human, Mouse, Rat
Immunogen:Human CSGALNACT2
Form:Liquid
Storage Buffer:PBS with 0.1% Sodium Azide, 50% Glycerol, pH 7.3. -20°C, Avoid freeze / thaw cycles.
Purification Method:Antigen Affinity purified
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Synonyms:chondroitin sulfate N-acetylgalactosaminyltransferase 2;CSGALNACT2;CSGalNAcT-2;DKFZp686H13226;FLJ43310;GALNACT-2;GALNACT2;MGC40204;PRO0082 ;
UniProt Protein Function:GALNACT2: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Belongs to the chondroitin N- acetylgalactosaminyltransferase family. 2 isoforms of the human protein are produced by alternative splicing.
UniProt Protein Details:

Protein type:Glycan Metabolism - chondroitin sulfate biosynthesis; Transferase; Membrane protein, integral; EC 2.4.1.174

Chromosomal Location of Human Ortholog: 10q11.21

Cellular Component: Golgi membrane; membrane; integral to Golgi membrane

Molecular Function:acetylgalactosaminyltransferase activity; metal ion binding; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity

Biological Process: chondroitin sulfate metabolic process; dermatan sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; chondroitin sulfate biosynthetic process; glycosaminoglycan metabolic process; proteoglycan biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process; carbohydrate metabolic process; pathogenesis; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process

NCBI Summary:This gene encodes a member of the chondroitin N-acetylgalactosaminyltransferase family. The encoded protein is involved in elongation during chondroitin sulfate synthesis. A related pseudogene has been identified on chromosome X. [provided by RefSeq, Dec 2012]
UniProt Code:Q8N6G5
NCBI GenInfo Identifier:60391915
NCBI Gene ID:55454
NCBI Accession:Q8N6G5.1
UniProt Secondary Accession:Q8N6G5,Q6MZJ5, Q6MZP6, Q8TCH4, Q9P1I6, B3KWL7,
UniProt Related Accession:Q8N6G5
Molecular Weight:38,440 Da
NCBI Full Name:Chondroitin sulfate N-acetylgalactosaminyltransferase 2
NCBI Synonym Full Names:chondroitin sulfate N-acetylgalactosaminyltransferase 2
NCBI Official Symbol:CSGALNACT2  
NCBI Official Synonym Symbols:CHGN2; PRO0082; GALNACT2; GALNACT-2  
NCBI Protein Information:chondroitin sulfate N-acetylgalactosaminyltransferase 2; beta 4 GalNAcT-2; chondroitin beta1,4 N-acetylgalactosaminyltransferase 2
UniProt Protein Name:Chondroitin sulfate N-acetylgalactosaminyltransferase 2
UniProt Synonym Protein Names:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 2; Beta4GalNAcT-2; GalNAcT-2
Protein Family:Chondroitin sulfate N-acetylgalactosaminyltransferase
UniProt Gene Name:CSGALNACT2  
UniProt Entry Name:CGAT2_HUMAN

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