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CSGALNACT1 Antibody (PACO22266)

SKU:
PACO22266
Product Type:
Antibody
Reactivity:
Human
Mouse
Host Species:
Rabbit
Isotype:
IgG
Applications:
ELISA
IHC
Antibody Type:
Polyclonal Antibody
Conjugation:
Unconjugated
€419
Frequently bought together:

Description

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CSGALNACT1 Antibody (PACO22266)

The CSGALNACT1 Polyclonal Antibody (PAC02266) is a valuable tool for researchers studying CSGALNACT1, an enzyme involved in the biosynthesis of glycosaminoglycans. This antibody, generated in rabbits, exhibits high specificity and sensitivity for detecting CSGALNACT1 in human samples, making it suitable for use in Western blot applications.CSGALNACT1, also known as chondroitin sulfate N-acetylgalactosaminyltransferase 1, plays a crucial role in the post-translational modification of proteoglycans, which are essential components of the extracellular matrix.

Dysregulation of CSGALNACT1 expression has been linked to various diseases, including cancer and neurological disorders, highlighting its importance in cellular processes.By utilizing the CSGALNACT1 Polyclonal Antibody in their research, scientists can gain insights into the function and regulation of CSGALNACT1, facilitating the development of targeted therapies for diseases associated with aberrant glycosaminoglycan metabolism. This antibody is a valuable resource for investigators working in the fields of glycobiology, oncology, and neuroscience.

Antibody Name:CSGALNACT1 Antibody (PACO22266)
Antibody SKU:PACO22266
Size:100ul
Host Species:Rabbit
Tested Applications:ELISA, IHC
Recommended Dilutions:ELISA:1:2000-1:10000, IHC:1:50-1:100
Species Reactivity:Human, Mouse
Immunogen:Synthesized peptide derived from internal of human CSGALNACT1.
Form:Liquid
Storage Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol.
Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen.
Clonality:Polyclonal
Isotype:IgG
Conjugate:Non-conjugated
Product ImageImmunohistochemistry analysis of paraffin-embedded human breast carcinoma tissue using CSGALNACT1 antibody.
Background:Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP-GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage.
Synonyms:Chondroitin ;
UniProt Protein Function:ChGn: Transfers 1,4-N-acetylgalactosamine (GalNAc) from UDP- GalNAc to the non-reducing end of glucuronic acid (GlcUA). Required for addition of the first GalNAc to the core tetrasaccharide linker and for elongation of chondroitin chains. Important role in chondroitin chain biosynthesis in cartilage. Belongs to the chondroitin N- acetylgalactosaminyltransferase family. 3 isoforms of the human protein are produced by alternative splicing.Protein type: Transferase; Membrane protein, integral; Glycan Metabolism - chondroitin sulfate biosynthesis; EC 2.4.1.174Chromosomal Location of Human Ortholog: 8p21.3Cellular Component: Golgi membrane; intracellularMolecular Function: acetylgalactosaminyltransferase activity; glucuronosyl-N-acetylgalactosaminyl-proteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; glucuronosyltransferase activity; glucuronylgalactosylproteoglycan 4-beta-N-acetylgalactosaminyltransferase activity; peptidoglycan glycosyltransferase activityBiological Process: chondroitin sulfate biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process; chondroitin sulfate proteoglycan biosynthetic process, polysaccharide chain biosynthetic process; dermatan sulfate proteoglycan biosynthetic process; proteoglycan biosynthetic process; UDP-glucuronate metabolic process; UDP-N-acetylgalactosamine metabolic process
UniProt Protein Details:
NCBI Summary:
UniProt Code:Q8TDX6
NCBI GenInfo Identifier:308153425
NCBI Gene ID:55790
NCBI Accession:Q8TDX6.2
UniProt Secondary Accession:Q8TDX6,Q6P9G6, Q8IUF9, Q9NSQ7, Q9NUM9, B2RBE4
UniProt Related Accession:Q8TDX6
Molecular Weight:33,917 Da
NCBI Full Name:Chondroitin sulfate N-acetylgalactosaminyltransferase 1
NCBI Synonym Full Names:chondroitin sulfate N-acetylgalactosaminyltransferase 1
NCBI Official Symbol:CSGALNACT1  
NCBI Official Synonym Symbols:ChGn; CSGalNAcT-1; beta4GalNAcT  
NCBI Protein Information:chondroitin sulfate N-acetylgalactosaminyltransferase 1
UniProt Protein Name:Chondroitin sulfate N-acetylgalactosaminyltransferase 1
UniProt Synonym Protein Names:Chondroitin beta-1,4-N-acetylgalactosaminyltransferase 1; Beta4GalNAcT-1
Protein Family:Chondroitin sulfate N-acetylgalactosaminyltransferase
UniProt Gene Name:CSGALNACT1  
UniProt Entry Name:CGAT1_HUMAN
Antibodies
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