The CSF3R Polyclonal Antibody (CAB7661) is a valuable tool for researchers studying the CSF3R protein, a receptor involved in regulating the production and function of neutrophils, a type of white blood cell important for immune response. This antibody, produced in rabbits, is highly specific to human samples and has been validated for use in Western blot applications.CSF3R, also known as granulocyte colony-stimulating factor receptor, plays a crucial role in stimulating the growth and differentiation of neutrophils in response to infection or injury. Dysregulation of CSF3R signaling has been implicated in various diseases, including leukemia and other hematological disorders.
By utilizing the CSF3R Polyclonal Antibody, researchers can gain valuable insights into the expression and activity of CSF3R in different cell types and tissues. This antibody enables the detection and analysis of CSF3R, facilitating studies in immunology, hematology, and cancer research. Understanding the function of CSF3R is essential for developing novel therapeutic strategies targeting neutrophil regulation and immune response modulation in various disease states.
Product Name:
CSF3R Rabbit Polyclonal Antibody
SKU:
CAB7661
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human
Immunogen:
A synthetic peptide corresponding to a sequence within amino acids 650-750 of human CSF3R (NP_000751.1).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
92kDa
Observed MW:
102kDa
The protein encoded by this gene is the receptor for colony stimulating factor 3, a cytokine that controls the production, differentiation, and function of granulocytes. The encoded protein, which is a member of the family of cytokine receptors, may also function in some cell surface adhesion or recognition processes. Alternatively spliced transcript variants have been described. Mutations in this gene are a cause of Kostmann syndrome, also known as severe congenital neutropenia.
Purification Method:
Affinity purification
Gene ID:
1441
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CSF3R antibody (CAB7661) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
