The CSF3 Polyclonal Antibody (CAB6178) is a valuable tool for research involving CSF3, also known as granulocyte colony stimulating factor (G-CSF), a cytokine that stimulates the production of neutrophils in the bone marrow. This antibody, raised in rabbits, is highly specific to human CSF3 and has been validated for use in various applications, including Western blot and immunohistochemistry.CSF3 plays a vital role in regulating the immune response, particularly in promoting the development and function of neutrophils, which are essential for combating bacterial and fungal infections.
Dysregulation of CSF3 has been linked to various diseases, including leukemia and severe infections, making it an important target for research in immunology and oncology.By utilizing the CSF3 Polyclonal Antibody, researchers can detect and analyze the expression of CSF3 in different cell types and tissues, allowing for a better understanding of its role in immune function and disease pathology. This antibody is a valuable asset for studies focusing on immune regulation, hematopoiesis, and the development of novel therapies for immune-related disorders.
Product Name:
CSF3 Rabbit Polyclonal Antibody
SKU:
CAB6178
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 30-207 of human CSF3 (NP_000750.1).
This gene encodes a member of the IL-6 superfamily of cytokines. The encoded cytokine controls the production, differentiation, and function of granulocytes. Granulocytes are a type of white blood cell that are part of the innate immune response. A modified form of this protein is commonly administered to manage chemotherapy-induced neutropenia. Alternatively spliced transcript variants have been described for this gene.
Purification Method:
Affinity purification
Gene ID:
1440
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of various lysates using CSF3 Rabbit pAb (CAB6178) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Enhanced Kit (AbGn00021).Exposure time: 90s.
