The CSF2RA Polyclonal Antibody (CAB2034) is a vital tool for researchers studying the CSF2RA protein, which is involved in immune regulation and inflammatory responses. This polyclonal antibody, raised in rabbits, exhibits high reactivity with human samples and has been validated for Western blot applications.CSF2RA, also known as GM-CSF receptor alpha subunit, plays a crucial role in immune function by binding to granulocyte-macrophage colony-stimulating factor (GM-CSF) and regulating the development and activation of immune cells. Dysregulation of CSF2RA has been linked to various inflammatory diseases and autoimmune conditions, making it a promising target for therapeutic interventions.
By using the CSF2RA Polyclonal Antibody, researchers can detect and analyze the CSF2RA protein in different cell types, providing valuable insights into its role in immune response modulation and potential implications in disease pathology. This antibody is a valuable tool for studies in immunology, cancer research, and inflammatory conditions, offering a deeper understanding of the complex mechanisms underlying immune regulation.
Product Name:
CSF2RA Rabbit Polyclonal Antibody
SKU:
CAB2034
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 23-320 of human CSF2RA (NP_758448.1).
Cell membrane, Secreted, Single-pass type I membrane protein.
Calculated MW:
46kDa
Observed MW:
80kDa
The protein encoded by this gene is the alpha subunit of the heterodimeric receptor for colony stimulating factor 2, a cytokine which controls the production, differentiation, and function of granulocytes and macrophages. The encoded protein is a member of the cytokine family of receptors. This gene is found in the pseudoautosomal region (PAR) of the X and Y chromosomes. Multiple transcript variants encoding different isoforms have been found for this gene, with some of the isoforms being membrane-bound and others being soluble.
Purification Method:
Affinity purification
Gene ID:
1438
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.02% sodium azide,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CSF2RA antibody (CAB2034) at 1:1000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 10s.
