The CSF1 Polyclonal Antibody (CAB1627) is specifically designed for research involving CSF1, a cytokine that plays a crucial role in the regulation of the immune system, particularly in the differentiation and function of macrophages. This antibody, produced in rabbits, exhibits high reactivity with human samples and has been validated for use in Western blot applications.By binding to the CSF1 protein, this antibody allows for the detection and analysis of CSF1 in various cell types, making it an ideal tool for studies in immunology, cancer research, and inflammatory conditions. CSF1 is a key player in macrophage development and function, making it an important target for understanding the immune system's response in diseases such as cancer, autoimmune disorders, and chronic inflammation.
Research involving the CSF1 Polyclonal Antibody (CAB1627) can provide valuable insights into the role of CSF1 in immune regulation and its potential therapeutic implications in various disease contexts. This antibody serves as a valuable tool for researchers aiming to further explore the mechanisms of immune response modulation and develop targeted therapies for immune-related disorders.
Product Name:
CSF1 Rabbit Polyclonal Antibody
SKU:
CAB1627
Size:
20uL, 100uL
Isotype:
IgG
Host Species:
Rabbit
Reactivity:
Human,Mouse,Rat
Immunogen:
Recombinant fusion protein containing a sequence corresponding to amino acids 33-190 of human CSF1 (NP_757351.1).
Cell membrane, Secreted, Single-pass type I membrane protein, extracellular space.
Calculated MW:
60kDa
Observed MW:
80kDa
The protein encoded by this gene is a cytokine that controls the production, differentiation, and function of macrophages. The active form of the protein is found extracellularly as a disulfide-linked homodimer, and is thought to be produced by proteolytic cleavage of membrane-bound precursors. The encoded protein may be involved in development of the placenta. Alternate splicing results in multiple transcript variants.
Purification Method:
Affinity purification
Gene ID:
1435
Storage Buffer:
Store at -20℃. Avoid freeze / thaw cycles.Buffer: PBS with 0.01% thimerosal,50% glycerol,pH7.3.
Western blot analysis of extracts of various cell lines, using CSF1 antibody (CAB1627) at 1:3000 dilution.Secondary antibody: HRP Goat Anti-Rabbit IgG (H+L) (CABS014) at 1:10000 dilution.Lysates/proteins: 25μg per lane.Blocking buffer: 3% nonfat dry milk in TBST.Detection: ECL Basic Kit (AbGn00020).Exposure time: 90s.
